Bailey lab is in the Department of Pathology and Laboratory Medicine at Brown University. The laboratory is mainly focused on the genetic variation in immunity and disease from both host and pathogen interaction. The laboratory is also interested in the role of variation of the malaria parasite on Burkitt Lymphoma a major childhood cancer found in malaria endemic areas, a disease known to be caused by Plasmodium falciparum and Epstein Barr Virus.
Together with other collaborators the team work on Type 1 Diabetes looking at T-cell receptor variation; they are also involved in optimizing methods for detection of Babesiosis a distant relative of the Plasmodium parasite.
The lab is headed by Prof Jeff Bailey an Associate Professor of Translational research. His research is an integrated one, combining experimental and computational approaches. The majority of his research focuses on the malaria parasite infection, parasite genome structure and tracking the spread of drug resistance. He has made major contributions to methods analysing whole genome sequencing in particular studying segmental duplication and copy number variation. He has more recently developed a high through-put pathogen targeted sequencing to track pathogens across space and time.